by Kevin Craig
- At No. 149 in the world, Bjorn Fratangelo became the lowest ranked player to take a set off of Novak Djokovic since No. 174 Nicolas Almagro, who was returning from injury at the time, won the second set in their meeting in Rome in May of 2015. The last time Djokovic lost a first set to a player outside of the Top 100 was when he dropped the first set to No. 158 Lleyton Hewitt in the 2012 Olympics.
- 18 year old Americans Taylor Fritz and Frances Tiafoe did battle in the first round in Indian Wells with Tiafoe wining in three sets. It was the first all-teen matchup in Indian Wells since Marin Cilic defeated Kei Nishikori in 2008.
- With Borna Coric and Alex Zverev reaching the third round in Indian Wells, it marks the first time since 2007 that multiple teenagers made the third round of the event. Djokovic, Andy Murray, and Evgeny Korolev were the players who did so.
- For the first time since 2010 in Indian Wells, no German woman reached the third round of the event.
- The No. 1 doubles seed in Indian Wells lost in the first round for the first time since 1998 as Jean-Julien Rojer and Horia Tecau lost to Lukasz Kubot and Marcin Matkowski, 10-6 in a match tiebreak.
- The final of the Jonkoping challenger lasted two hours and 44 minutes, making it the longest final on the challenger circuit in 2016. Andrey Golubev took home the title by beating Karen Khachanov, 6-7(9), 7-6(5), 7-6(4), saving four match points along the way. The four match points saved was the most in a challenger final since Tim Smyczek saved four in the Tiburon Challenger in 2015.
- The challenger event in Santiago saw a 19-year age difference in the first round as 38 year old Ruben Ramirez Hidalgo took on 19 year old Christian Garin. Ramirez Hidalgo came out with the victory in three sets.
- Facundo Bagnis became the first player to successfully defend a challenger title in 2016, winning the title in Santiago for the second straight year, also making it three titles in four tries in the Chilean capital.